Contents

6.1 The road to discovery of clinically relevant biomarkers for radiotherapy response

6.2 Is more research needed?
6.2.1 Patient numbers
6.2.2 Cutoff values
6.2.3 Interactions between factors
6.2.4 Prognostic vs. predictive factors

6.3 Rubbish in, rubbish out (quote Adrian C. Begg)
6.3.1 The pre-treatment sample
6.3.2 Just (messenger) RNA?
6.3.3 Need for adequate biomarkers of processes

6.4 How to individualize future treatment?

6.5 References