Acknowledgements

We thank Wim Brugman and Ron Kerkhoven for conducting the sequencing experiments and Iris de Rink for processing the mRNA sequencing data (all NKI Genomics Core Facility). We would like to acknowledge the NKI- AVL Core Facility Molecular Pathology & Biobanking (Dennis Peters, Annegien Broeks and Linde Braaf) for supplying NKI-AVL Biobank material and lab support. We thank Brad Wouters for his helpful suggestions.

Financial support

This study was partly funded by the Dutch Cancer Society (NKI-2007-3941) and the Verwelius foundation.